Home Forums General Discussion statistical trending for early phase clinical material

Viewing 2 posts - 1 through 2 (of 2 total)
  • Author
    Posts
  • ksparkman
    Participant
    Post count: 3

    What is everyone’s experience with applying the 95 % confidence interval to early phase clinical material, with limited lots? Do you apply it and how do you interpret the data?

    Walter Routh
    Moderator
    Post count: 37

    In my experience, we applied the 95% confidence interval to everything as a basis for making stability decisions and taking future actions. I can’t think of why any less stringent criterion would be applied to run into future dating issues (an the ire of a reviewer) and I can’t think of why tighter criterion would be beneficial, like shooting yourself in the foot. How to handle (interpret) a less than favorable statistical report would entirely depend on who/what is going to be consuming the material, then appropriate justification of that interpretation seems plausible, at least for the sake of continuing meaningful research.

Viewing 2 posts - 1 through 2 (of 2 total)
  • You must be logged in to reply to this topic.