By Julie Meneghel, Peter Kilbride, Bill Shingleton, Alex Nancekievill, John Morris, Cytiva
Published in: Cell & Gene
Published on: January 12, 2022
Introduction: For effective delivery of many cell therapies, a cryogenic cold chain is essential. However, cryopreservation can damage biologics if optimal cooling, storage, and thawing strategies are not used. While the traditional cooling agent for controlled-rate freezing in clean room settings is liquid nitrogen, there are challenges to meet cGMP guidelines by using liquid nitrogen in medicinal product manufacturing. To address these challenges, Cytiva’s range of VIA Freeze™ systems deliver liquid nitrogen-free controlled cooling for optimized, compliant cell cryopreservation.
