By Brian Pahl
Published in: AMI by Pfeiffer Vacuum
Published on: October 17, 2022
Introduction: The quality and effectiveness of drugs significantly depends on their proper packaging: It needs to be unscathed and of the highest quality. Otherwise, serious consequences might occur. This was proven by a serious incident in the 1970´s: During this period, contaminated intravenous fluids packaged in glass bottles - which were typical at the time for packaging such dosage forms - caused an estimated 2,000 to 8,000 episodes of bloodstream infection, resulting in the deaths of about 10% of the patients. This severe package-integrity failure incident has triggered a heightened awareness of package integrity.